Quick Answer
Win Set's shooting gallery to lose him temporarily; complete all four ARK quests to power the machine. Set is invincible while pursuing you through Buster HQ as you collect drones. Shoot down his bullets and reflect his larger projectile with a charged shot.
Final chapter: how do you shake off Set at Buster HQ?
Win Set's shooting gallery to interrupt his pursuit and give yourself time to collect drones. Use the Neo Junk City walkthrough for the surrounding chapter route.
Shoot down Set's projectiles
Destroy every projectile during his regular attacks. Each encounter includes 2 or 3 regular attacks before he throws a larger projectile.
Reflect the larger projectile
Use a charged shot against the larger projectile to bounce it back at Set. Winning this shooting gallery gets him off your back temporarily.
Resume collecting drones
Continue collecting drones around Buster HQ during the break in Set's pursuit. The shooting gallery gives you a temporary opening; Set remains invincible in this section.
For other encounters, use the Neo Junk City bosses guide.
What must you finish to power the machine?
Complete the four ARK quests for Spider, Bat, Hyena, and Lizard before starting the machine.
- Complete all four quests, checking Spider, Bat, Hyena, and Lizard against your progress.
- Start the final chapter's machine after all four quests are complete.
Use the ARK quests guide for those tasks. For the ending route involving the machine, continue with the Neo Junk City best ending guide.
What should you do when you get stuck?
Shoot Set's projectiles if his attacks stop you, and check all four ARK quests if the machine lacks power.
Set keeps catching you
Beat his shooting gallery to earn another temporary break from the pursuit. Focus on destroying his projectiles and returning the large one with a charged shot.
Cover does not work against Set. Set is invincible during the Buster HQ pursuit, so winning the shooting gallery only delays him.
The machine does not have enough power
Check completion of Spider, Bat, Hyena, and Lizard's ARK quests. All four are required to start the machine in the final chapter.
Reported by other guides, not verified
A cymbal monkey toy from the Scientist's lab arcade game is reported to lure Set when dropped. Players say the toy makes noise that draws him away.
FAQ
Set's shooting gallery gives temporary relief, while all four ARK quests are required to start the machine.
Set is invincible while pursuing you at Buster HQ. Winning his shooting gallery only gets him off your back temporarily.
Shoot down the projectiles from his 2 or 3 regular attacks. Hit the larger projectile with a charged shot to bounce it back at him.
Cover does not work against Set. Destroy his projectiles and reflect the larger one to win the shooting gallery.
The machine requires completion of all four ARK quests. Check the quests for Spider, Bat, Hyena, and Lizard.